陈红旗 博士 教授 博/硕导

办公室：礼勤楼935

实验室：礼勤楼929-930

Email: hq80chen@mail.ahnu.edu.cn

个人简历

• 2008-2012 上海交通大学 应用化学 工学博士

• 2002-2005 安徽师范大学 分析化学 理学硕士

• 1998-2002 淮北师范大学（淮北煤炭师范学院） 化学教育 理学学士

工作经历

• 2005-至今 安徽师范大学 助教 讲师 副教授 教授

主持项目

国家自然科学基金项目2项；安徽省自然科学基金项目1项；安徽省高等学校自然科学研究项目重大、重点、一般项目各1项；安徽省高校青年教师科研资助计划重点项目1项；芜湖市科技项目1项。

研究兴趣

• 上转换发光全内反射成像及超分辨成像

• 稀土上转换发光纳米材料的合成及其在光（电）传感、生物分析中的应用研究

讲授课程

• 本科生课程： 分析化学（I） 无机及分析化学 普通化学(I) 基础/综合化学实验

• 研究生课程： 发光与成像分析

获奖情况

安徽省科学技术奖二等奖 2019年 基于微纳界面的化学与生物传感分析及应用（2018-2-R2） (排名第二)

安徽省教学成果一等奖 2008年 在精品课程建设中切实强化本科生实践能力与创新意识的培养（2008031-3）(排名第三)

安徽省科学技术奖三等奖 2007年 有机纳米粒子的制备及其在分析中的应用（2007-3-R2）(排名第二)

学生获奖

研究生多次获得国家奖学金及一等学业奖学金

代表性论文

27. Hongqi Chen*, Ruoxin Wang, Juanjuan Cheng, Lun Wang， Hua He*. A ratiometric upconversion nanoprobe enables super-resolution imaging sensing of biothiols in living cells, Chemical Communications, 2024, DOI: 10.1039/D3CC06242B.

26. Xinhong Ye, Ruoxin Wang, Hongqi Chen*, Yufeng Wen*, Lun Wang*. Quantitative image analysis and cell imaging of peroxynitrite based on an upconversion luminescence total internal reflection single particle imaging platform, Sensors &Actuators: B. Chemical, 2022, 369: 132308.

25. Hongqi Chen*, Wei Tang, Yunchun Liu, Lun Wang*. Quantitative image analysis method for detection of nitrite with cyanine dye-NaYF₄:Yb,Tm@NaYF₄ upconversion nanoparticles composite luminescent probe, Food Chemistry, 2022, 367: 130660.

24. Wei Tang, Ruo Mi, Lun Wang*, Hongqi Chen*. Quantitative image analysis for sensing HIV DNAs based on NaGdF₄:Yb,Er@NaYF₄ upconversion luminescent probe and magnetic beads, Sensors &Actuators: B. Chemical, 2021, 340: 129969.

23. Yunchun Liu*, Wanru Zhu, Xinru Wei, Lun Wang, Hongqi Chen*. Cyanine dye-assembled composite upconversion nanoparticles for the sensing and cell imaging of nitrite based on a single particle imaging method, Analyst, 2022, 147: 2793-2801.

22. Hongqi Chen*, Wanying Xia, Qian Gao, Lun Wang*. Sensitive quantitative image analysis of bisulfite based on near-infrared upconversion luminescence total internal reflection platform, Talanta, 2021, 224: 121928.

21. Wanying Xia, Bo Ling, Lun Wang, Feng Gao*, Hongqi Chen*. A near-infrared upconversion luminescence total internal reflection platform for quantitative image analysis. Chemical Communications, 2020, 56, 8440-8443.

20. Hongqi Chen, Xueping Yang, Yunchun Liu*, Lun Wang *. Turn-on detection of glutathione S-transferase based on luminescence resonance energy transfer between near-infrared to near-infrared core-shell upconversion nanoparticles and organic dye, Analytical and Bioanalytical Chemistry, 2020, 412: 5843–5851.

19. Huihui Wang, Yunyun Lu, Lun Wang*, Hongqi Chen*. Detection of tyramine and tyrosinase activity using red region emission NaGdF₄:Yb,Er@NaYF₄ upconversion nanoparticles. Talanta, 2019, 197, 558-566.

18. Wen Wang，Mingying Zhao, Lun Wang*, Hongqi Chen*. Core-shell upconversion nanoparticles of type NaGdF₄:Yb,Er@NaGdF₄:Nd,Yb and sensitized with a NIR dye are a viable probe for luminescence determination of the fraction of water in organic solvents. Microchimica Acta, 2019, 186(9), 630.

17. Yunyun Lu, Lun Wang*, Hongqi Chen*. Turn-on detection of MicroRNA155 based on simple UCNPs-DNA-AuNPs luminescence energy transfer probe and duplex-specific nuclease signal amplification. Spectrochimica Acta Part A, 2019, 223, 117345.

16. Yaoyao Zhou, Bo Ling, Hongqi Chen*, Lun Wang*. Mn²⁺-doped NaYF₄:Yb,Er upconversion nanoparticles for detection of uric acid based on the Fenton reaction. Talanta, 2018, 180, 120-126.

15. Ni Gao, Bo Ling, Zhongling Gao, Lun Wang*, Hongqi Chen*. Near-infrared-emitting NaYF₄:Yb,Tm/Mn upconverting nanoparticle gold nanorod electrochemiluminescence resonance energy transfer system for sensitive prostate-specific antigen detection. Analytical and Bioanalytical Chemistry, 2017, 409, 2675–2683.

14. Keyi Cheng, Jianguo Zhang, Liping Zhang, Lun Wang*, Hongqi Chen*. Aptamer biosensor for Salmonella typhimurium detection based on luminescence energy transfer from Mn²⁺-doped NaYF₄:Yb, Tm upconverting nanoparticles to gold nanorods. Spectrochimica Acta Part A, 2017, 171, 168–173.

13. Liping Zhang, Bo Ling, Lun Wang*, Hongqi Chen*. A near-infrared luminescent Mn²⁺-doped NaYF₄:Yb,Tm/Fe³⁺ upconversion nanoparticles redox reaction system for the detection of GSH/Cys/AA. Talanta, 2017, 172, 95–101.

12. Jianguo Zhang, Shaozhen Wang, Ni Gao, Dexiang Feng, Lun Wang*, Hongqi Chen*. Luminescence energy transfer detection of PSA in red region based on Mn²⁺-enhanced NaYF₄:Yb,Er upconversion nanorods. Biosensors and Bioelectronics, 2015, 72, 282-287.

11. Fei Yuan, Hongqi Chen*, Juan Xu, YiYan Zhang, Yong Wu, Lun Wang*. Aptamer-based Luminescence Energy Transfer from Near-infrared-to-Near-infrared Upconverting Nanoparticles to Gold Nanorods and its application for the Detection of Thrombin, Chemistry A European Journal, 2014, 20, 2888–2894.

10. Hongqi Chen*, Yingying Guan, Shaozhen Wang, Yuan Ji, Mengqi Gong, Lun Wang*. Turn-On detection of a cancer marker based on near-infrared luminescence energy transfer from NaYF₄:Yb,Tm/NaGdF₄ core/shell upconverting nanoparticles to gold nanorods. Langmuir, 2014, 30 (43), 13085–13091.

9. Hongqi Chen, Fei Yuan, Shaozhen Wang, Juan Xu, YiYan Zhang, Hongqi Chen*. Aptamer-based sensing for thrombin in red region via Fluorescence Resonant Energy Transfer between NaYF₄:Yb,Er upconversion nanoparticles and gold nanorods, Biosensors Bioelectronics, 2013, 48, 19–25.

8. Hongqi Chen, Fei Yuan, Shao-Zhen Wang, Juan Xu, Yi-Yan Zhang, Lun Wang*. Near-infrared to Near-infrared Upconverting NaYF₄:Yb³⁺,Tm³⁺ Nanoparticles-Aptamer-Au nanorods Light Resonance Energy Transfer System for the Detection of Mercuric(II) Ions in solution, Analyst, 2013, 138, 2392-2397.

7. Hongqi Chen, Juan Xu, Fei Yuan, Yong Wu, Yiyan Zhang, Lun Wang*, A “turn-off” luminescence resonance energy transfer aptamer sensor based on near-infrared upconverting NaYF_4:Yb³⁺,Tm³⁺ nanoparticles as donors and gold nanorods as acceptors, Chinese Chemical Letters, 2013, 24(1), 79-81.

6. Hongqi Chen, Yong Wu, Fei Yuan, Juan Xu, Yiyang Zhang, Lun Wang*. Inner filter effect of gold nanoparticles on the fluorescence of rare-earth phosphate nanocrystals and its application for determination of biological aminothiols, Journal of Luminescence, 2013, 141, 33-37.

5. Hongqi Chen, Jicun Ren*. Selective detection of Fe²⁺ by combination of CePO₄:Tb³⁺ nanocrystal–H₂O₂ hybrid system with synchronous fluorescence scan technique. Analyst, 2012, 137, 1899-1903.

4. Hongqi Chen, Jicun Ren*. Sensitive determination of chromium (VI) based on the inner filter effect of upconversion luminescent nanoparticles (NaYF₄:Yb³⁺, Er³⁺), Talanta, 2012, 99, 404-408.

3. Hongqi Chen, Cailing Zhou，Lun Wang*, Jingguo Chen, Bo Ling, Jie Fu. Terbium (III) chelate complexes as fluorescence energy transfer donor in the determination of formaldehyde in aqueous solutions. Spectrochimica Acta Part A, 2011, 78, 371–374.

2. Hongqi Chen, Jie Fu, Lun Wang*, Bo Lin, Binbin Qian, Jingguo Chen, Cailing Zhou. Ultrasensitive mercury(II) ion detection by europium(III)-doped cadmium sulde composite nanoparticles. Talanta, 2010, 83, 139–144.

1. Hongqi Chen, Ani Liang, Lun Wang*, Yan Liu, Binbin Qian. Ultrasensitive determination of Cu²⁺ by synchronous fluorescence spectroscopy with functional nanoparticles. Microchimica Acta, 2009, 164, 453–458.

专 利

1. 陈红旗，周瑶瑶 柠檬酸盐修饰的上转换发光纳米粒子及其制备方法、葡萄糖的检测方法和应用, ZL201810377027.0

2. 陈红旗，郜中玲 二氧化锰纳米片修饰的上转换发光纳米材料及制备方法,过氧化氢或胆碱的检测方法及应用, ZL201710176343.7

3. 陈红旗，王慧慧 用于检测辣根过氧化物酶的上转换纳米粒子及其制备方法和辣根过氧化物酶的检测方法, ZL201910026746.2

4. 陈红旗，唐薇 Dye-UCNPs纳米探针及其制备方法以及亚硝酸盐的检测方法, ZL 202011121792.X.

5. 陈红旗，汪文 四氟硼酸亚硝修饰的上转换纳米粒子、纳米探针及其制备方法以及含硫化合物的检测方法, ZL201910921074.1

6. 陈红旗、郜中玲 二氧化锰纳米片修饰的上转换发光纳米材料及制备方法、过氧化氢或胆碱的检测方法及应用，ZL201710176343.7