王辉
王辉 教授 博士生导师
▸办公室：花津校区78mppt威九国际礼勤楼 516 室
▸实验室：花津校区78mppt威九国际礼勤楼 509-510 室
▸Email: wanghui29085@ahnu.edu.cn
教育背景
▸2007.09-2011.07 郑州大学 理学学士 化学 （导师：崔秀灵教授）
▸2011.09-2014.07 郑州大学 理学硕士 有机化学 （导师：崔秀灵教授、吴养洁院士）
▸2014.10-2019.03 德国哥廷根大学 理学博士 有机化学 （导师：Prof. Dr. Lutz Ackermann）
工作经历
▸2019.04-2019.08 德国哥廷根大学 博士后 有机化学 （导师：Prof. Dr. Lutz Ackermann）
▸2019.09-2022.01 英国布里斯托大学 博士后 有机化学 （导师：Prof. Varinder Kumar Aggarwal）
▸2022.03-至今 安徽师范大学
主持项目和荣誉
▸德国DFG博士后研究项目 (442129649), 项目负责人 (https://gepris.dfg.de/gepris/projekt/442129649), 2020.02-2022.01
▸安徽师范大学博士科研启动基金, 项目负责人, 2022.03-2025.02
▸国家自然科学基金青年科学基金项目 (22201010), 项目负责人, 2023.01-2025.12
▸安徽省高等学校科研计划优秀青年项目 (2022AH030024), 项目负责人, 2022.12-2025.11
▸安徽省海外引才计划青年项目 (2023)
▸安徽省自然科学基金优秀青年项目 (2308085Y09), 项目负责人，2023.09.01-2026.08.31
▸教育部第一批博士后海外引才专项, 项目负责人，2024.01.01-2026.12.31
▸人社部高层次留学人才回国资助, 项目负责人，2024.1.1-2026.12.31
研究领域
▸过渡金属催化合成方法学研究
▸可见光诱导的自由基反应研究
▸有机硼化合物的合成与转化研究
荣誉与获奖
▸德国博士毕业学位等级最高等 (Summa Cum Laude), 2019
▸河南省优秀硕士论文, 2014
学术成果
1) H. Balati, J. Zhu, W. Xu, H. Wang,* X. Hu,* Z. Ruan,* Solvent-Regulated Electrochemical Selenylation and Deuteration of Alkynyl Aryl Ketones: Chemoselective Synthesis of 3-Selenylated Chromones and Deutero-Selenylated Chalcones. Adv. Synth. Catal. 2023, DOI: 10.1002/adsc.202300512.
2) H. Wang,+ W. Han,+ A. Noble, V. K. Aggarwal,* Dual Nickel/Photoredox-Catalyzed Site-selective Cross-Coupling of 1,2-Bis-Boronic Esters Enabled by 1,2-Boron Shifts. Angew. Chem. Int. Ed. 2022, 61, e202207988.
3) H. Wang, J. Wu, A. Noble, V. K. Aggarwal,* Selective Coupling of 1,2-Bis-Boronic Esters at the more Substituted Site through Visible-Light Activation of Electron Donor-Acceptor Complexes. Angew. Chem. Int. Ed. 2022, 61, e202202061.
4) H. Wang,+ C. Jing,+ A. Noble, V. K. Aggarwal,* Stereospecific 1,2‐Migrations of Boronate Complexes Induced by Electrophiles. Angew. Chem. Int. Ed. 2020, 59, 16859–16872.
5) H. Wang,+ N. Kaplaneris,+ L. Ackermann, Allenes in Manganese(I)-Catalyzed C–C Activation and A Strategy for Cascade Ring-Expansion. Cell Rep. Phys. Sci. 2020, 1, 100178.
6) H. Wang,+ I. Choi,+ T. Rogge, N. Kaplaneris, L. Ackermann,* Versatile and Robust C–C Activation by Chelation-Assisted Manganese-Catalysis. Nature Catal. 2018, 1, 993–1001.
7) H. Wang,+ F. Pesciaioli,+ J. C. A. Oliveira, S. Warratz, L. Ackermann,* Synergistic Manganese(I) C−H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation. Angew. Chem. Int. Ed. 2017, 56, 15063–15067.
8) H. Wang,+ M. M. Lorion,+ L. Ackermann,* Air-Stable Manganese(I)-Catalyzed C–H Activation for Decarboxylative C–H/C–O Cleavages in H2O. Angew. Chem. Int. Ed. 2017, 56, 6339–6342.
9) H. Wang,+ M. M. Lorion,+ L. Ackermann,* Overcoming the Limitations of C−H Activation with Strongly Coordinating N-Heterocycles by Cobalt Catalysis. Angew. Chem. Int. Ed. 2016, 55, 10386–10390. (Highlight by Synfacts 2016, 12, 1126)
10) H. Wang, M. M. Lorion, L. Ackermann,* Domino C–H/N–H Allylations of Imidates by Cobalt Catalysis. ACS Catal. 2017, 7, 3430–3433.11)
11) H. Wang, M. Moselage, M. J. González, L. Ackermann,* Selective Synthesis of Indoles by Cobalt(III)-Catalyzed C−H/N−O Functionalization with Nitrones. ACS Catal. 2016, 6, 2705–2709.
12) H. Wang, J. Koeller, W. Liu, L. Ackermann,* Cobalt(III)-Catalyzed C–H/N–O Functionalizations: Isohypsic Access to Isoquinolines. Chem. Eur. J. 2015, 21, 15525–15528.
13) H. Wang, X. Cui,* Y. Pei, Q. Zhang, J. Bai, D. Wei, Y. Wu,* Direct Regioselective Phosphonation of Heteroaryl N-oxides with H-phosphonates under Metal and External Oxidant Free Conditions. Chem. Commn. 2014, 50, 14409–14411.
14) H. Wang, Y. Pei, J. Bai, J. Zhang, Y. Wu,* X. Cui,* Dimerization of Heteroaromatic N-oxides Under Metal-Free Conditions. RSC Adv. 2014, 4, 26244–26246.
15) A. Çapcı, M. M. Lorion, H. Wang, N. Simon, M. Leidenberger, M. C. Borges Silva, D. R. M. Moreira, Z. Yongping, M. Yuqing, C. J. Yun, Y. M. Lee, O. Friedrich, B. Kappes, J. Wang, L. Ackermann,* S. B. Tsogoeva,* Artemisinin‐(Iso)Quinoline Hybrids by C‐H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria. Angew. Chem. Int. Ed. 2019, 58, 13066–13079.
16) N. Kaplaneris, T. Rogge, R. Yin, H. Wang, G. Sirvinskaite, L. Ackermann,* Late-Stage Diversification by Manganese-Catalyzed C–H Activation: Access to Acyclic, Hybrid and Stapled Peptides. Angew. Chem. Int. Ed. 2019, 58, 3476–3480.
17) S. R. Yetra, Z. Shen, H. Wang, L. Ackermann,* Thiocarbonyl-Enabled Ferrocene C–H Nitrogenation by Cobalt(III) Catalysis: Thermal and Mechanochemical. Beilstein J. Org. Chem. 2018, 14, 1546–1553.
18) R. Mei, H. Wang, S. Warratz, S. A. Macgregor, L. Ackermann,* Cobalt-Catalyzed Oxidase C–H/N–H Alkyne Annulation: Mechanistic Insights and Access to anti-Cancer Agents. Chem. Eur. J. 2016, 22, 6759–6763.
19) Q. Zhang, X. Cui,* L. Zhang, S. Luo,* H. Wang, Y. Wu,* Redox Tuning of a Direct Asymmetric Aldol Reaction, Angew. Chem. Int. Ed. 2015, 54, 5210–5213.
20) Q. Zhang, D. Wei, X. Cui,* D. Zhang, H. Wang, Y. Wu,* Direct Diphosphonylation of Quinolines with H-phosphonates under Metal-Free Conditions, Tetrahedron 2015, 71, 6087–6093.
21) J. Bai, X. Cui,* H. Wang, Y. Wu,* Copper-Catalyzed Reductive Coupling of Aryl Sulfonyl Chlorides with H-phosphonates Leading to S-aryl Phosphorothioates, Chem. Commun. 2014, 50, 8860–8863.
22) H. Zhang, X. Cui,* X. Yao, H. Wang, J. Zhang, Y. Wu*, Directly Fused Highly Substituted Naphthalenes via Pd-Catalyzed Dehydrogenative Annulation of N,N-Dimethylaminomethyl Ferrocene Using a Redox Process with a Substrate. Org. Lett. 2012, 14, 3012–3015.